?580 Confederacy of the Fudul formed in Mecca to counterbalance more powerful clans

?585-590 War of Fijar - Quraysh involved in a breach of a sacred month in fighting Bedouin

?590 'Uthman b. Huwayrith attempts (in vain) to lead Mecca under Byzantine paramountcy

?590 Muhammad marries Khadijah; four daughters from this marriage

610 (or earlier) Muhammad has first revelation

613 (or earlier) First public preaching

615 (or earlier) Emigration of some Muslims to Abyssinia

616-619 (or earlier) Boycott of the Banu Hashim

?617 Battle of Bu'ath at Yathrib (Medina) - stalemate between 'Aws and Khazraj groups

?619 Death of Khadijah and Abu-Talib; Muhammad seeks support in Ta'if

621 First agreement at 'Aqabah with Medinan converts

622 Larger agreement at 'Aqabah, and Hijrah to Medina

624 Expedition of Nakhlah, first bloodshed; Battle of Badr, Muslim victory against odds; Qaynuqa' Jews expelled from Medina

625 Battle of Uhud: Quraysh fail to suppress Medina despite a victory; Jews of al-Nadir expelled

626 First expedition to Dumat al-Jandal, between Syria and the Iraq

627 Meccans besiege Medina (campaign of al-Khandaq, the Ditch); Qurayzah Jews are massacred

628 Treaty of Hudaybiyah: truce with Quraysh; Khaybar Jews are subjugated

629 Peaceful pilgrimage to Mecca; first expedition to Mu'tah, toward Ghassan territory on Syrian border, following Sasanian evacuation

630 Muslims occupy Mecca; defeat Bedouin at Hunayn; temporarily abandon siege of Ta'if; massive expeidition to Tabuk south of Syria, against Ghassan

631 Deputations from many parts of Arabia accepting Islam, including Ta'if and the Sasanid-connected Yemen

632 Muhammad's "farewell" pilgrimage; Musaylimah appears as prophet in Yamanah in central Arabia; Muhammad's death